Day 1 (21 Aug 2024)

DAY 1 - 21 AUGUST 2024 (WEDNESDAY)

8.30am - 9.00am (SGT)

Registration

9.00am - 9.15am (SGT)

Welcome Address

Grand Ballroom

Prof Patrick Tan

Precision Health Research, Singapore

Opening Address by Guest of Honour

Grand Ballroom

Dr Janil Puthucheary

Senior Minister of State, Ministry of Digital Development and Information, and Ministry of Health

9.15am - 9.45am (SGT)

Plenary Talk 1

Grand Ballroom

NHS Genomic Medicine Service – From Cohorts to Clinics

Prof Dame Sue Hill

NHS England

9.45am - 10.15am (SGT)

Teabreak Networking Session

Session 1

10.15am - 11.40am (SGT)

Ethics and Policy

This session aims to update researchers on the ethical and legal considerations as well as the implications surrounding data sharing and data analysis of an individual's genetic and genomic information.

Grand Ballroom

Polygenic Risk Scores and Reproduction: Ethical, Legal and Social Issues

Prof Julian Savulescu

National University of Singapore

Who is ELSA? Why does ELSI matter?!

Dr Michaela Mayrhofer

BBMRI-ERIC

Diversity, representation and bias in precision medicine

Dr Angela Ballantyne

University of Otago

Moderator

Prof Nicki Tiffin

South African National Bioinformatics Institute, University of the Western Cape

11.40am - 12.00pm (SGT)

Poster Session

Grand Ballroom & Foyer

12.00pm - 1.30pm (SGT)

Parallel Track 1: Lunch Time Industry Talk

Grand Ballroom

Presentation by PacBio

Personalized Medicine with PacBio Long Reads: Experience from the Estonian Biobank

Prof Lili Milani

Estonia Biobank, Estonian Genome Center, University of Tartu

Presentation by MGI

Empowering Clinical Insights with Advanced DNBSEQ Solutions for Population Genomics

Dr Radoje (Rade) Drmanac

MGI Tech

Parallel Track 2: Lunch Time Industry Talk

Meeting Room

Presentation by BC Platforms

Maximising the use of existing RWD for the benefit of your diverse patient population; A Clinical use case demonstrating the value of true federation network

Mr Nino da Silva

BC Platforms

Presentation by SomaLogic

Scaling proteomics for translational medicine: Can it be done while preserving performance?

Dr Stephen A. Williams

SomaLogic

Parallel Track 3: Oral Presentations (Early Career Investigators)

Wisteria & Camellia Villa

Presenter 1:

From cohorts to the clinic: interactively visualising amyotrophic lateral sclerosis (ALS) future risk projections

Dr Jane Ong Siying

Singapore Institute of Clinical Sciences, Agency for Science, Technology and Research

Presenter 2:

Predicting early-life BMI Trajectories through Proteomics Data by learning Parametric Koopman Decomposition

Dr Chen Yurui

Department of Mathematics, National University of Singapore, and Singapore Institute for Clinical Sciences, Agency for Science, Technology and Research

Presenter 3:

Metabolome-wide association of carotid intima media thickness in an Asian population cohort identifies FDX1 as a determinant of cholesterol metabolism and cardiovascular risk.

Dr Nilanjana Sadhu

Lee Kong Chian School of Medicine, Nanyang Technological University

Presenter 4:

Integrative analysis of omics summary data reveals putative mechanisms underlying dilated cardiomyopathy

Konstanze Tan

Lee Kong Chian School of Medicine, Nanyang Technological University

Presenter 5:

Vasculature damage and dysmetabolism in heart failure with preserved ejection fraction.

Wu Lik Hang

National University of Singapore

Session 2

1.30pm - 2.00pm (SGT)

Plenary Talk 2

Grand Ballroom

Singapore National Precision Medicine Programme - Value Creation for Health and the Economy

Prof Patrick Tan

Precision Health Research, Singapore

2.00pm - 3.20pm (SGT)

Parallel Track 1: Data Driven Discovery

This session aims to highlight research discoveries accelerated by the advent of big data and global data sharing and collaboration among longitudinal population studies.

Grand Ballroom

Our Future Health: A world leading resource for population health, genomics and prevention research

Dr Raghib Ali

Our Future Health

Decoding Cellular Intelligence To Accelerate Drug Discovery

Dr Rob Yang

CartaBio Inc

Advancing Genomic Medicine through Global Data Sharing and Collaboration

Dr Heidi Rehm

Massachusetts General Hospital and Broad Institute

Moderator

Dr Thomas Keane

EMBL- European Bioinformatics Institute

Parallel Track 2: Complex Traits/Variant Resolution

This session aims to discuss traits and diseases that are affected by multiple genes and environmental influences. Analytical techniques for associating specific genetic variants with complex traits will be demonstrated.

Meeting Room

Single-cell RNA-seq dataset integration without loss of unique rare cell populations

Prof Wong Limsoon

National University of Singapore

Realising the Dream of Precision Medicine in Schizophrenia

Dr Jimmy Lee

Institute of Mental Health

Beyond Single-Trait Analysis: Assessing Type 2 Diabetes Genetic Risk in a Middle Eastern Population

Dr Ammira Al-Shabeeb Akil

Sidra Medicine

Moderator

Dr Lim Weng Khong

Duke-NUS Medical School

3.20pm - 4.00pm (SGT)

Teabreak Networking Session

Session 3

4.00pm - 5.20pm (SGT)

Parallel Track 1: Cancer Genetics

This session aims to inform healthcare professionals on recent discoveries related to the genetic basis of various cancers, and discuss the use of novel diagnostic tools to treat patients with the appropriate therapeutics.

Grand Ballroom

Cancer Predisposition in Singapore: Insights from SG10K and beyond

Prof Joanne Ngeow

National Cancer Centre Singapore

Integrating Cohorts and Multi-Omics to Capture the Earliest Determinants of Cancer and Aging

Dr Philip Awadalla

Ontario Institute for Cancer Research

Genetic Risk Assessment in Cancer: Towards Personalized Risk Management in Asian Populations

Dr Ho Weang Kee

University of Nottingham Malaysia/Cancer Research Malaysia

Moderator

Dr Arash Etemadi

National Cancer Institute, NIH

Parallel Track 2: Genomic Screening

This session aims to explore the use of genomic analysis technologies to deliver prognoses for both common and rare genetic diseases and what are the implications of the applications.

Meeting Room